Overdose Drug Facts | 0 comments Someone would have to smoke over 1,500 pounds of marijuana within about 15 minutes to die of a lethal overdose. In other words, dying from a weed overdose is nearly impossible. Fact source Submit a Comment Cancel reply Your email address will not be published. Required fields are marked *Comment Name * Email * Website This site uses Akismet to reduce spam. Learn how your comment data is processed.